$730.00
One product does it all: Say goodbye to tedious maintenance and easily conquer Hong Kong's climate.
Do you find daily skincare too complicated, or are you hesitant to go to a beauty salon because you're not good at skincare or afraid of going?
Meanwhile, Hong Kong's humid, hot, and changeable climate poses a severe challenge to your skin, making it prone to problems such as water-oil imbalance, enlarged pores, sensitivity, and dullness.
Dr.Once, a regenerative beauty skincare brand originating from Japan, brings you solutions with the ultimate cost-effectiveness. It seamlessly integrates professional beauty technology into your daily routine.
This serum is perfectly suited to Hong Kong's climate, allowing for rapid penetration and reaching deep into the skin! Whether you're a skincare beginner or a "lazy person" seeking high efficiency and convenience, you can easily enjoy "salon-level" deep repair and care effects at home, bidding farewell to skin problems caused by climate and transforming into a confident and beautiful woman!
Japanese SNS is very popular
Dr.Once Quad-Core Microneedle Serum perfectly combines groundbreaking microneedle explosion technology with four top-tier Japanese ingredients to initiate comprehensive repair at the skin's root.
Double the absorption rate of your serum, delivering effects deep into your skin.
The " Dr.Once Quad-Core Microneedle Serum" infuses four of the most advanced and highly regarded ingredients in the medical aesthetics industry— exosomes (purple), retinol (red), vitamin C (yellow), and azelaic acid (green) —into four serums using exclusive microneedle penetration technology. This set is a top-tier skincare solution designed for those seeking ultimate, highly effective, and comprehensive skin improvement !
✦ Daily Vitamin C
✦ Nighttime Exosome
✦ Daytime Exosome
✦ Nighttime Retinol
✦ Daytime Azelaic Acid
✦ Nighttime Exosome/Retinol
[Top-tier technology guaranteed]
All four serums utilize NEEDLE SHOT SERUM microneedle delivery technology to ensure that every drop of active ingredient can penetrate the skin's surface efficiently and stably, maximizing its effectiveness.
Whether you're looking for whiter, firmer, more stable, or repaired skin, the "Quad-Core Microneedle Serum" is the only answer to achieving perfect skin.
Why is Dr.Once Exosome right for you?
As a current hot topic in beauty technology
The main advantages of Exosome serum lie in its powerful repairing, anti-aging, and moisturizing effects. It can promote the proliferation of collagen and elastin, making the skin firm and elastic; it can also improve dullness, brighten skin tone, soothe redness and sensitivity, and strengthen the skin barrier function. Due to its nano-sized molecules, it can effectively penetrate deep into the skin, thereby achieving a more comprehensive skin improvement effect.
✦ Exosomes are tiny vesicles with a diameter of about 30 to 150 nanometers. You can think of them as "miniature parcels" or "cell messengers" that transmit messages between cells.
✦ These tiny vesicles contain a wealth of signaling molecules, including growth factors, which guide cell growth and repair.
✦ Proteins and lipids: Involved in the regulation of cell structure and function.
Dr.Once products do not rely solely on the single function of exosomes; rather, they utilize carefully selected potent ingredients to create synergistic skincare formulas, making the serums even more effective.
✦ As the core "cellular messenger", it transmits regeneration and repair instructions from the root, activates collagen production, and achieves deep anti-aging and repair.
✦ A well-known anti-aging molecule that effectively boosts cellular energy and aids in activating cellular metabolism. When NMN binds to exosomes, it helps provide sufficient energy to cells that receive regeneration signals, accelerating the repair process.
✦ A powerful antioxidant, its main function is to scavenge free radicals and protect cells from environmental stress and oxidative damage. Glutathione helps maintain the stability of active ingredients such as exosomes and provides a purer, healthier microenvironment for repaired cells.
✦ These growth factors directly provide precise growth signals to cells. Combined with the indirect command transmission from exosomes, they can provide dual stimulation to fibroblasts, maximizing the skin's regenerative capacity.
Why is Dr. Once Retinol right for you?
✦ Definition of Retinol ✦
Retinol is a fat-soluble vitamin belonging to the vitamin A family. It is recognized in the skincare industry as one of the most effective anti-aging ingredients and is classified as a retinoid.
Retinol itself is mild. After it is absorbed by the skin, it needs to go through a series of transformation processes to finally become a biologically active form—retinoic acid—before it can work at the cellular level.
✦ Retinyl acid can stimulate collagen production in the dermis and inhibit collagen breakdown. This helps improve skin elasticity, reduce fine lines and wrinkles, and make the skin firmer and plumper.
✦ Retinol can accelerate the renewal and metabolism of epidermal cells (Cell Turnover). This helps remove dead skin cells, improves skin texture, and makes the skin smoother and more delicate.
✦ By regulating the secretion of sebaceous glands and accelerating the metabolism of the stratum corneum, retinol can effectively prevent clogged pores and has a significant effect on improving acne (pimples, acne) and shrinking enlarged pores.
✦ It accelerates cell renewal and helps with the metabolism and shedding of melanin, thus having a certain auxiliary effect on improving dullness, brightening overall skin tone, and fading pigmentation or spots.
Dr.Once's retinol products do not rely solely on Vitamin A; instead, they utilize a sophisticated complex formula to maximize the effectiveness of retinol while simultaneously addressing repair and stability.
✦ As a core anti-aging and skin-renewing ingredient, it is responsible for promoting collagen production, accelerating cell metabolism, and improving wrinkles and rough skin texture.
✦ A well-known anti-aging molecule that effectively boosts cellular energy and aids in activating cellular metabolism. When NMN binds to exosomes, it helps provide sufficient energy to cells that receive regeneration signals, accelerating the repair process.
✦ A powerful antioxidant, its main function is to scavenge free radicals and protect cells from environmental stress and oxidative damage. Glutathione helps maintain the stability of active ingredients such as exosomes and provides a purer, healthier microenvironment for repaired cells.
✦ These growth factors directly provide precise growth signals to cells. Combined with the indirect command transmission from exosomes, they can provide dual stimulation to fibroblasts, maximizing the skin's regenerative capacity.
Why is Dr. Once Vitamin C right for you?
Vitamin C (scientific name: ascorbic acid) is an essential water-soluble vitamin and is recognized in the beauty and skincare industry as one of the most important antioxidants.
It has multiple and significant benefits for the skin:
✦ Vitamin C is a powerful antioxidant that effectively neutralizes free radicals and protects skin cells from damage caused by environmental pollution, UV radiation, and oxidative stress. This helps slow down the photoaging process and maintain healthy skin.
✦ Vitamin C can interfere with the melanin production process, especially by inhibiting the activity of tyrosinase. Therefore, it can effectively: fade existing dark spots, acne scars, and pigmentation; even out and brighten the overall skin tone; and improve dull skin.
✦ Vitamin C is an important cofactor in the collagen synthesis process. It can stimulate skin fibroblasts to produce new collagen, thereby: improving skin elasticity and firmness; reducing fine lines and wrinkles; and achieving an anti-aging effect.
✦ Vitamin C works synergistically with other antioxidants such as Vitamin E to enhance the skin's self-repair capabilities, helping to repair damaged cells and strengthen the skin barrier. In summary, Vitamin C is an all-around skincare star, combining antioxidant, brightening, and anti-aging benefits.
Dr.Once's Vitamin C products use a complex formula that cleverly combines multiple highly effective ingredients to overcome the tendency of Vitamin C to be easily deactivated, and to maximize its whitening, antioxidant, and anti-aging effects:
✦ As the core high-efficiency antioxidant and whitening ingredient, it is mainly responsible for neutralizing free radicals, brightening skin tone, fading pigmentation, and stimulating collagen synthesis.
✦ A well-known anti-aging molecule that effectively boosts cellular energy and aids in activating cellular metabolism. When NMN binds to exosomes, it helps provide sufficient energy to cells that receive regeneration signals, accelerating the repair process.
✦ A powerful antioxidant, its main function is to scavenge free radicals and protect cells from environmental stress and oxidative damage. Glutathione helps maintain the stability of active ingredients such as exosomes and provides a purer, healthier microenvironment for repaired cells.
✦ These growth factors directly provide precise growth signals to cells. Combined with the indirect command transmission from exosomes, they can provide dual stimulation to fibroblasts, maximizing the skin's regenerative capacity.
Why is Dr. Once azelaic acid right for you?
Azelaic acid is a common ingredient in beauty products and has many benefits for the skin, especially for those with acne-prone skin, pimples, and uneven skin tone.
The following are the main benefits of azelaic acid in beauty products:
✦ It has antibacterial properties, which can inhibit the growth of acne-causing bacteria (such as Propionibacterium acnes) and help reduce acne formation.
It helps dissolve dead skin cells and unclog pores, reducing hair follicle blockage and thus improving acne and blackheads.
✦ It can inhibit the activity of tyrosinase, a key enzyme in the production of melanin.
It helps to fade acne scars (post-inflammatory hyperpigmentation), age spots, and melasma, resulting in a more even and radiant complexion.
✦ It has anti-inflammatory properties and can help reduce redness and discomfort of the skin.
It is commonly used to treat redness and papules caused by rosacea.
Dr.Once's azelaic acid products combine highly effective anti-inflammatory and purifying ingredients with a variety of cutting-edge active ingredients to create a complex formula that can repair problem skin from multiple angles:
✦ As the core cleansing and conditioning ingredients, it is mainly responsible for inhibiting acne bacteria, resisting inflammation, improving acne and clogged pores, and effectively fading acne marks and pigmentation.
✦ A well-known anti-aging molecule that effectively boosts cellular energy and aids in activating cellular metabolism. When NMN binds to exosomes, it helps provide sufficient energy to cells that receive regeneration signals, accelerating the repair process.
✦ A powerful antioxidant, its main function is to scavenge free radicals and protect cells from environmental stress and oxidative damage. Glutathione helps maintain the stability of active ingredients such as exosomes and provides a purer, healthier microenvironment for repaired cells.
✦ These growth factors directly provide precise growth signals to cells. Combined with the indirect command transmission from exosomes, they can provide dual stimulation to fibroblasts, maximizing the skin's regenerative capacity.
Say goodbye to exorbitant medical aesthetic prices and enjoy a seamless, age-reversing rejuvenation at home!
✦ Double Approach: Natural Beauty Injections + Beauty Serum ✦
Dr.Once Microneedling Serum [Peak Value for Money] Say goodbye to exorbitant medical aesthetic prices and enjoy a flawless, age-reversing rejuvenation experience at home!
The product combines "natural beauty needles" to create nano-level channels, while using "ultimate beauty ingredients" (such as exosomes/retinol) to "rapidly penetrate" deep into the stratum corneum.
✦ Achieve a radiant, medical-grade complexion ✦
Microneedling and Gold Implantation Technology Unlock the Ultimate in Hydration ✨
Microneedling precisely opens the skin's absorption channels, while gold nanoparticles deeply penetrate and deliver active ingredients, reaching the skin's base layer in a second. This dual-technology approach provides continuous hydration and repair.
Maximum absorption!
✦ Topical Microneedling Technology ✦
Skincare ingredients penetrate deeply into the skin effectively
The microneedle serum uses topical microneedling technology. The natural microneedles contain beauty essence ingredients that can gently penetrate the stratum corneum to penetrate the skin, promote deep skin absorption, and stimulate collagen production.
Originating from Japan, this product utilizes medical-grade technology to awaken the true beauty of your skin.
Dr.Once is committed to bringing clinic-level "precision repair" into your home using leading scientific methods, unleashing your skin's true potential from the inside out.
We carefully select the world's top ingredients and combine them with "medical-grade innovative formulas" to comprehensively support your skin in achieving its optimal, rejuvenated state. Each product is an ultimate "at-home medical-grade experience." We promise that with every use, you will personally witness the amazing transformation and wonder of your skin.
Firmness and elasticity
User Empirical Evidence
My skin feels firmer.
More flexible.
Fine lines and smoothness
User Approval
Fine lines are visibly smoothed after use.
Skin feels smoother and more delicate.
Absorption effect
User authentication
The absorption speed and penetration of skincare products are significantly improved.
luster and complexion
User Feedback
After use, skin becomes brighter, complexion improves, and radiates a natural glow.
*The above information and data are based on feedback from 50 users who personally tested the product.
◇Passed patch testing (not all users will experience skin irritation).
Dr.Once Topical Serum
Do you yearn for the remarkable results of medical-grade aesthetic treatments, but are concerned about the "recovery period," "pain," and "high cost" of injections?
Dr.Once topical serum brings you a revolutionary, all-around integrated effect, allowing you to easily enjoy top-notch repair at home every day!
Starting today, our "at-home skincare" program will be upgraded to "at-home medical-grade aesthetic treatments."
5-star reviews from Japanese users
Multiple additive-free formulas reduce irritation.
Step 1. After cleansing, take an appropriate amount into the palm of your hand and gently apply.
Step 2. Repeat application for areas of particular concern.
Step 3. After completion, you can proceed with your usual skincare routine.
* Avoid using this product around the eyes and lips. * When using this product, be sure to take sun protection measures when going out.
※A slight tingling sensation may be felt during use; this is a normal reaction as the active ingredients take effect.
※The stinging sensation will subside after a while. If the irritation persists, rinse with clean or warm water.
Use it immediately after cleansing! The key is to use it as the first step in your skincare routine, and then continue with your regular skincare steps.
✅ Press 1-2 pumps into the palm of your hand.
✅ Apply gently to the skin, avoiding the eye and lip areas.
✅ It is recommended to use it on areas that require special care.
Available at all Mannings stores
